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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMS1
All Species:
9.39
Human Site:
S423
Identified Species:
18.79
UniProt:
P54277
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54277
NP_000525.1
932
105830
S423
F
G
Y
G
H
C
S
S
E
I
S
N
I
D
K
Chimpanzee
Pan troglodytes
XP_515987
1061
120272
S552
F
G
Y
G
H
C
S
S
E
I
S
N
I
D
K
Rhesus Macaque
Macaca mulatta
XP_001103074
831
93641
K378
N
K
M
E
S
S
G
K
N
Y
S
N
V
D
T
Dog
Lupus familis
XP_536002
930
105612
S423
H
C
D
D
H
F
N
S
E
N
S
N
I
D
K
Cat
Felis silvestris
Mouse
Mus musculus
P54279
859
95207
N402
P
V
P
G
K
Q
D
N
S
P
S
L
K
S
T
Rat
Rattus norvegicus
NP_001009535
919
103710
I423
F
S
G
E
Y
S
H
I
N
K
D
T
F
Q
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507554
871
92244
D414
P
P
D
G
I
P
P
D
N
T
P
P
D
S
P
Chicken
Gallus gallus
NP_001006508
916
103017
E419
T
V
H
S
C
L
E
E
K
E
A
S
K
N
D
Frog
Xenopus laevis
NP_001079545
925
103654
E423
E
V
A
Y
S
E
N
E
T
F
D
G
F
L
V
Zebra Danio
Brachydanio rerio
NP_958476
896
98728
S414
E
D
W
V
I
N
R
S
D
L
D
S
I
N
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188203
734
80915
N281
T
K
V
L
L
Q
N
N
D
A
V
I
C
L
I
Poplar Tree
Populus trichocarpa
XP_002321013
915
101109
D425
E
E
K
F
M
M
K
D
F
A
L
R
L
H
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.4
86.2
83.6
N.A.
22.3
73.7
N.A.
35.9
58.3
50.7
46.1
N.A.
N.A.
N.A.
N.A.
28.3
Protein Similarity:
100
87.7
87.7
92.6
N.A.
41.6
86
N.A.
50.7
74.6
69
64.6
N.A.
N.A.
N.A.
N.A.
45.8
P-Site Identity:
100
100
20
53.3
N.A.
13.3
6.6
N.A.
6.6
0
0
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
26.6
60
N.A.
20
13.3
N.A.
6.6
33.3
6.6
46.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
23.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
45.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
0
0
0
17
9
0
0
0
0
% A
% Cys:
0
9
0
0
9
17
0
0
0
0
0
0
9
0
9
% C
% Asp:
0
9
17
9
0
0
9
17
17
0
25
0
9
34
9
% D
% Glu:
25
9
0
17
0
9
9
17
25
9
0
0
0
0
0
% E
% Phe:
25
0
0
9
0
9
0
0
9
9
0
0
17
0
0
% F
% Gly:
0
17
9
34
0
0
9
0
0
0
0
9
0
0
9
% G
% His:
9
0
9
0
25
0
9
0
0
0
0
0
0
9
0
% H
% Ile:
0
0
0
0
17
0
0
9
0
17
0
9
34
0
9
% I
% Lys:
0
17
9
0
9
0
9
9
9
9
0
0
17
0
25
% K
% Leu:
0
0
0
9
9
9
0
0
0
9
9
9
9
17
0
% L
% Met:
0
0
9
0
9
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
9
25
17
25
9
0
34
0
17
9
% N
% Pro:
17
9
9
0
0
9
9
0
0
9
9
9
0
0
9
% P
% Gln:
0
0
0
0
0
17
0
0
0
0
0
0
0
9
0
% Q
% Arg:
0
0
0
0
0
0
9
0
0
0
0
9
0
0
0
% R
% Ser:
0
9
0
9
17
17
17
34
9
0
42
17
0
17
0
% S
% Thr:
17
0
0
0
0
0
0
0
9
9
0
9
0
0
17
% T
% Val:
0
25
9
9
0
0
0
0
0
0
9
0
9
0
9
% V
% Trp:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
17
9
9
0
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _